citrate

acetyl-CoA

oxaloacetate

ATP-citrate lyase

ATP-citrate lyase

RAC-alpha serine/threonine-protein kinase

RAC-alpha serine/threonine-protein kinase

ATP

ADP

Pi

Histone
acetylation

Phosphatidylinositol 3-kinase regulatory subunit

ATP-citrate lyase

ATP-citrate lyase

Sterol regulatory element-binding protein 1

Tyrosine-protein kinase receptor

Phosphatidylinositol 3-kinase regulatory subunit

Sterol regulatory element-binding protein 1

coenzyme A