Reactome-Recon List 2

This list includes proteins from Recon2 that are also involved in the complexes that participate in signalling processes in Reactome pathways as reactants or products. Table 2a includes phosphorylation processes, while Tables 2b and 2c include other types of processes.

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Table 2a. Signalling phosphorylation processes & Recon2 compounds-catalysers

UniProt	HGNC	Reactome processes	MRegAtlas
Q9NY65	TUBA8	Phosphorylation of cohesin by PLK1 at centromeres
P09622	DLD	BCKDK phosphorylates BCKDH

Table 2b. Other signalling processes & Recon2 compounds-catalysers

UniProt	HGNC	Reactome processes	MRegAtlas
P06865	HEXA	Hexosaminidase A cleaves GalNAc from GM2 to form GM3
P08559	PDHA1	PDK-catalyzed phosphorylation (inactivation) of PDC E1 alpha subunit
P51970	NDUFA8	Intermediate 1 binds HP subcomplex to form Intermediate 2
P31350	RRM2	RNR (M1M2) reduces nucleotide diphosphates to deoxynucleotide diphosphates (glutaredoxin)
O95299	NDUFA10	Intermediate 1 binds HP subcomplex to form Intermediate 2
O75251	NDUFS7	NUBPL transfers 4Fe-4S to Complex I subunits
Q9NY65	TUBA8	ERGIC-to-Golgi vesicles bind dynein:dynactin
Q96RQ3	MCCC1	HLCS biotinylates MCCC1:MCCC2
P08195	SLC3A2	Basigin binds CD98 complex
P31040	SDHA	Transfer of electrons through the succinate dehydrogenase complex
P08574	CYC1	Electron transfer from ubiquinol to cytochrome c of complex III
P15291	B4GALT1	Association of ADAM and B4GALT1 With ZP3
P47985	UQCRFS1	Electron transfer from ubiquinol to cytochrome c of complex III
Q16795	NDUFA9	Intermediate 1 binds HP subcomplex to form Intermediate 2
P07686	HEXB	Hexosaminidase A cleaves GalNAc from GM2 to form GM3
P09622	DLD	PDK-catalyzed phosphorylation (inactivation) of PDC E1 alpha subunit

Table 2c. Expression signalling processes & Recon2 compounds-catalysers

UniProt	HGNC	Reactome processes	MRegAtlas
O00763	ACACB	Expression of Acetyl CoA Carboxylase 2 (ACACB, ACC2)	Acyl-carnitine
P11310	ACADM	Expression of ACADM
P49748	ACADVL	Expression of ACADVL