Regulation of eicosanoid production

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References

  1. Adler DH, Cogan JD, Phillips JA 3rd, Schnetz-Boutaud N, Milne GL, Iverson T, Stein JA, Brenner DA, Morrow JD, Boutaud O, Oates JA. Inherited human cPLA(2alpha) deficiency is associated with impaired eicosanoid biosynthesis, small intestinal ulceration, and platelet dysfunction. J Clin Invest. 2008 Jun;118(6):2121-31. doi: 10.1172/JCI30473. PMID: 18451993.
  2. Leslie CC. Cytosolic phospholipase A2: physiological function and role in disease. J Lipid Res. 2015 Aug;56(8):1386-402. doi: 10.1194/jlr.R057588. PMID: 25838312.
  3. Lin LL, Wartmann M, Lin AY, Knopf JL, Seth A, Davis RJ. cPLA2 is phosphorylated and activated by MAP kinase. Cell. 1993 Jan 29;72(2):269-78. doi: 10.1016/0092-8674(93)90666-e. PMID: 8381049.
  4. Smith WL, Urade Y, Jakobsson PJ. Enzymes of the cyclooxygenase pathways of prostanoid biosynthesis. Chem Rev. 2011 Oct 12;111(10):5821-65. doi: 10.1021/cr2002992. PMID: 21942677.

Contributors

Alexander Mazein1,2, Maria del Carmen Heredia3

Affiliations
  1. 1Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg
  2. 2Department of Cancer Research, Luxembourg Institute of Health, Strassen, Luxembourg
  3. 3University of Connecticut School of Medicine, Farmington, USA