Regulation of nitric oxide production - iNOS pathway

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References

  1. Bogdan C. Nitric oxide synthase in innate and adaptive immunity: an update. Trends Immunol. 2015 Mar;36(3):161-78. doi: 10.1016/j.it.2015.01.003. PMID: 25687683.
  2. Ganster RW, Taylor BS, Shao L, Geller DA. Complex regulation of human inducible nitric oxide synthase gene transcription by Stat 1 and NF-kappa B. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8638-43. doi: 10.1073/pnas.151239498. PMID: 11438703.
  3. Gao J, Morrison DC, Parmely TJ, Russell SW, Murphy WJ. An interferon-gamma-activated site (GAS) is necessary for full expression of the mouse iNOS gene in response to interferon-gamma and lipopolysaccharide. J Biol Chem. 1997 Jan 10;272(2):1226-30. doi: 10.1074/jbc.272.2.1226. PMID: 8995425.
  4. Kamijo R, Harada H, Matsuyama T, Bosland M, Gerecitano J, Shapiro D, Le J, Koh SI, Kimura T, Green SJ, et al. Requirement for transcription factor IRF-1 in NO synthase induction in macrophages. Science. 1994 Mar 18;263(5153):1612-5. doi: 10.1126/science.7510419. PMID: 7510419.
  5. Qualls JE, Subramanian C, Rafi W, Smith AM, Balouzian L, DeFreitas AA, Shirey KA, Reutterer B, Kernbauer E, Stockinger S, Decker T, Miyairi I, Vogel SN, Salgame P, Rock CO, Murray PJ. Sustained generation of nitric oxide and control of mycobacterial infection requires argininosuccinate synthase 1. Cell Host Microbe. 2012 Sep 13;12(3):313-23. doi: 10.1016/j.chom.2012.07.012. PMID: 22980328.
  6. SBGN Bricks: SBGN Bricks library. sbgnbricks.sourceforge.net.

Contributors

Alexander Mazein1,2, Maria del Carmen Heredia3

Affiliations
  1. 1Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg
  2. 2Department of Cancer Research, Luxembourg Institute of Health, Strassen, Luxembourg
  3. 3University of Connecticut School of Medicine, Farmington, USA