Reactome-Recon lists

Reactome-Recon lists were generated automatically using a combination of two resources: the Reactome Neo4j graph database (Fabregat et al., 2018, PMID: 29377902) and the Human Metabolic Network Reconstruction Recon2 (Thiele et al., 2013, PMID: 23455439), combined in one Neo4j graph database.

Reactome-Recon List 1 - Proteins

The list includes proteins that Recon2 lists as enzymes on their own.

Reactome-Recon List 2 - Complexes

This list includes proteins that Recon2 lists as parts of enzyme complexes.

References

  1. Fabregat A, Korninger F, Viteri G, Sidiropoulos K, Marin-Garcia P, Ping P, Wu G, Stein L, D’Eustachio P, Hermjakob H. Reactome graph database: Efficient access to complex pathway data. PLoS Comput Biol. 2018 Jan;14(1):e1005968. doi: 10.1371/journal.pcbi.1005968. PMID: 29377902.
  2. Thiele I, Swainston N, Fleming RM, Hoppe A, Sahoo S, Aurich MK, Haraldsdottir H, Mo ML, Rolfsson O, Stobbe MD, Thorleifsson SG, Agren R, Bölling C, Bordel S, Chavali AK, Dobson P, Dunn WB, Endler L, Hala D, Hucka M, Hull D, Jameson D, Jamshidi N, Jonsson JJ, Juty N, Keating S, Nookaew I, Le Novère N, Malys N, Mazein A, Papin JA, Price ND, Selkov E, Sigurdsson MI, Simeonidis E, Sonnenschein N, Smallbone K, Sorokin A, van Beek JH, Weichart D, Goryanin I, Nielsen J, Westerhoff HV, Kell DB, Mendes P, Palsson BØ. A community-driven global reconstruction of human metabolism. Nat Biotechnol. 2013 May;31(5):419-25. doi: 10.1038/nbt.2488. PMID: 23455439.